ES-NDD is developed to allow users explore essential sites in the structure of neurodevelopmental disorder (NDD) associated proteins. Essential sites represents residues in proteins that are conserved across human paralog proteins, constraint of missense mutations and are enriched for pathogenic variants in the 3D structure.

Disclaimer: Please note that all content on this website is provided for academic and research purposes only. It has not undergone clinical validation, and should not be used for medical advice, diagnosis, or treatment